Reaction Investigation

Safety is the number one priority in the blood system in Canada. The Office of Provincial Renal, Transplant and Transfusion Services of Manitoba Health helps make sure Manitoba’s blood supply is safe by supervising a surveillance program and supporting training and education programs.

Transfusion Transmitted Injuries Surveillance System

The 1997 Report of the Commission of Inquiry on the Blood System in Canada (Krever Commission) led to a series of initiatives and enhanced funding to improve the safety of Canada’s blood supply. One initiative, for reporting adverse transfusion events, is the Transfusion Transmitted Injuries Surveillance System (TTISS). The Public Health Agency of Canada (PHAC) leads this program. TTISS began as a pilot project in 1999 and is now a national program that monitors transfusion reactions in Canada.

Hospitals report adverse transfusion reactions voluntarily. Reporting allows the monitoring of known transfusion risks and new transfusion risks in the blood supply. The aim of the surveillance system is to improve transfusion processes and patient safety in Canada.

Transfusion reaction investigation process in Manitoba

The Manitoba Transfusion Expert Community has developed best practices for the treatment and laboratory investigation of transfusion reactions in Manitoba.

Provincial status

Manitoba has actively participated in TTISS. Continuing participation in TTISS is a goal of the Office of Provincial Renal, Transplant and Transfusion Services of Manitoba Health.

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